Cow-Calf Corner
Do injection site swellings and lesions indicate decrease in vaccine response?

 
University of Arkansas beef specialists conducted an experiment to compare the clostridial antibody response of 8 month-old heifers that do develop OR do not develop visible injection-site lesions and swelling.  Blood samples were collected on day 0, 28, 56, 84, and 112 after injection with a 7-way clostridial subcutaneous vaccination.  The vaccinations were given in the neck with a pistol-grip syringe using the tented technique.  Heifers with lesions (64.9%) actually had elevated antibody titers for Clostridial chauvoei (blackleg) on day 28 and day 84 compared to heifers without lesions or swelling.  Clostridium sordelli and Clostridium perfringens antibody titers were higher in heifers with lesions on day 28 and day 56.  Consequently, the presence of an injection-site lesion or swelling following a clostridial vaccination may not have visual appeal but may have positive implications for immune response.  Source: Troxel and co-workers. 2001 University of Arkansas Animal Science Research Report.
.
 

 

Return to Cow/Calf Corner